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Eli Lilly says experimental drug slows Alzheimer’s worsening

Published Wed, 27 Nov 2024 13:56:07 GMT

WASHINGTON (AP) — Eli Lilly and Co. said Wednesday its experimental Alzheimer’s drug appeared to slow worsening of the mind-robbing disease in a large study.In the 18-month trial, people in the early stages of Alzheimer’s who received infusions of donanemab showed 35% less decline in thinking skills compared to those given a dummy drug, Lilly announced in a press release. The drug is designed to target and clear away a sticky protein called beta-amyloid that builds up into brain-clogging plaques that are one hallmark of Alzheimer’s. A similar amyloid-targeting drug, Eisai and Biogen’s Leqembi, recently hit the market with similar evidence that it could modestly slow Alzheimer’s — and also some safety concerns, brain swelling or small brain bleeds.Donanemab also comes with that risk. Lilly said in its study, the brain side effects caused the deaths of two participants and a third also died after a serious case.The preliminary study results haven’t been vetted by outside experts. Indi...

“Estaba tan asustado como yo”: Director de escuela relata encuentro cara a cara con un oso

Published Wed, 27 Nov 2024 13:56:07 GMT

Un oso negro le dio una gran llamada de atención a un director de West Virginia cuando salió, gruñendo y rugiendo, de un contenedor de basura afuera de una escuela primaria.El director de la Escuela Primaria Zela, James Marsh, se sorprendió al descubrir que el oso de alguna manera logró ingresar al contenedor de basura durante el fin de semana, incluso después de que la escuela instaló una barra de seguridad. Mientras Marsh abría el contenedor el lunes, el oso comenzó a abrir la tapa.“Eso despertará a una persona”, expresó Marsh el martes en una entrevista telefónica. “Eso fue a las 7:15 a.m., si aún no estás despierto, eso te despertará”.Según muestra el video, Marsh salió disparado una vez que apareció la cabeza del oso. Luego, el oso saltó y salió corriendo en un encuentro que fue grabado por una cámara de seguridad de la escuela y desde entonces se ha compartido ampliamente en las redes sociales.“Parecía que también estaba asustado, tan asustado como yo”, indicó Marsh. “Puede qu...

13 charges filed against suspects in deadly rock-throwing spree

Published Wed, 27 Nov 2024 13:56:07 GMT

JEFFERSON COUNTY, Colo. (KDVR) — Colorado District Attorney Alexis King announced official charges Wednesday morning against the suspects accused in the deadly rock-throwing spree.Joseph Koenig, Nicholas "Mitch" Karol-Chik and Zachary Kwak have been charged with 13 different counts in relation to the rock-throwing spree that killed 20-year-old Alexa Bartell on April 19. Rock-throwing suspect said they were ‘blood brothers’ after spree, documents show Koenig, Karol-Chik, and Kwak are facing the following charges:One count of first-degree murder with extreme indifferenceSix counts of criminal attempt to commit first-degree murderThree counts of second-degree assaultThree counts of criminal attempt to commit second-degree assault“We thank the Jefferson County Sheriff’s Office for their investigation and the community for their commitment to identifying the suspects. Based on the available facts and after careful legal analysis, we have filed charges and will now move forward with a c...

Did you know you could get caught speeding by an aircraft?

Published Wed, 27 Nov 2024 13:56:07 GMT

CASTLE ROCK, Colo. (KDVR) — Did you know that you could get caught speeding by an aircraft flying above the roadway? It's true, and Colorado State Patrol handed out quite a few tickets from the skies on Tuesday.CSP operates multiple Cessna aircraft that it uses to monitor traffic on Colorado highways. The planes fly about 1,500 feet above the ground watching drivers on Interstate 70, Interstate 25, C-470 and other major highways.Pilots then monitor a vehicle’s speed using thick white strips painted or placed on road surfaces. Each mark is exactly half a mile apart. What happens if you get a red light ticket in Denver? If you have ever driven by one of those signs that read, "Speed checked by aircraft" and thought it was just a scare tactic, CSP in Castle Rock is reminding drivers it's not.On Tuesday, CSP said they issued 18 citations in just two hours in the area of I-25 and Greenland using aircraft.According to CSP, it is common to spot speeders driving anywhere between 80 and 10...

BSO releases identity of suspect who shot man in Lauderdale Lakes Walmart

Published Wed, 27 Nov 2024 13:56:07 GMT

A news release delivered by the Broward Sheriff’s Office revealed the identity of the shooter who terrorized Walmart employees and customers after he shot and killed a man.BSO deputies identified the suspect as 22-year-old Tironie Sterling and he is being charged with murder during the commission of a felony and robbery by sudden snatching. He’s expected to appear in court, on Wednesday afternoon.According to the news release, Sterling was off-duty from working at the Walmart where he opened fire to meet with a female co-worker. They got into an argument which escalated to a physical encounter where Sterling dropped his firearm on the floor and attempted to steal the Walmart employee’s phone. As the altercation escalated even further, a customer tried to interfere in an attempt to help the woman. This led to Sterling getting into a dispute with the customer.Sterling shot the Good Samaritan several times before fleeing the scene. The customer was then airlifted to t...

Astronomers observe star swallowing planet for first time — and it’s the size of Jupiter

Published Wed, 27 Nov 2024 13:56:07 GMT

(CNN) — In a world first, scientists have observed the moment that a dying star consumed a planet — a fate that eventually awaits Earth.While astronomers have previously seen planets just before and just after being engulfed by a star, this is the first time that a planetary demise has been observed, according to a team of scientists from the Massachusetts Institute of Technology, Harvard University and the California Institute of Technology.“The fact that the solar system planets would get engulfed into the sun in the future was something I had read first in high school, so it was surreal to realize that we may have found the first ever example of catching a similar event in real time!” study lead author Kishalay De, a postdoctoral researcher at Massachusetts Institute of Technology, told CNN.The process sees a star billow out to a million times its original size as it runs out of fuel, engulfing any matter in its wake. Astronomers observed this as a white-hot fla...

Chipotle celebrates Cinco De Mayo with Partiful platform

Published Wed, 27 Nov 2024 13:56:07 GMT

Chipotle is celebrating five days of Cinco De Mayo on an event platform that has become popular with Gen Z users. The promotion started on May 1 and will last until May 5.Partiful, a platform where users can organize an event with ease, has collaborated with Chipotle to offer BOGO deals to the first 20 people who tag @Chipotle and send their event link to Chipotle via Instagram. This is an effort to get customers to introduce their friends and family who have never tried Chipotle. People interested in entering the sweepstakes can do so here.Chipotle is also offering free delivery to customers who order online through their website or mobile app. Foodies can use the promo code CINCO23 to indulge in the offer.

10-year-old children were found working at a Louisville McDonald’s until 2 a.m.

Published Wed, 27 Nov 2024 13:56:07 GMT

(CNN) — Two 10-year-old children were found working at a Louisville McDonald’s restaurant — sometimes until 2 a.m. — the US Department of Labor said Tuesday.The revelation was part of an investigation into the child labor law violations in the Southeast. The agency also found three franchisees that own more than 60 McDonald’s locations in Kentucky, Indiana, Maryland and Ohio, “employed 305 children to work more than the legally permitted hours and perform tasks prohibited by law for young workers,” the Labor Department said in a statement.The franchisees, Bauer Food, Archways Richwood and Bell Restaurant Group, did not immediately respond to a request for comment. CNN has also reached out to McDonald’s for comment.“Investigators from the department’s Wage and Hour Division found two 10-year-old workers at a Louisville McDonald’s restaurant among many violations of federal labor laws committed by three Kentucky McDonald’s fr...

US had no warning of a drone attack on the Kremlin, officials say

Published Wed, 27 Nov 2024 13:56:07 GMT

The Biden administration had no foreknowledge of an impending drone attack on the Kremlin, four U.S. officials said, and a top official recommends caution when it comes to Moscow’s claims.Russia said Wednesday that two drones flew overnight into the heart of Moscow to assassinate President Vladimir Putin, even though he wasn’t in the complex. Kyiv denies the allegation and officials said Ukraine had nothing to do with the attack. Instead, they insist it’s all a pretext created by the Kremlin to escalate its 14-month war.Secretary of State Antony Blinken said he’d take anything coming from the Kremlin with a “large shaker of salt” during a conversation with the Washington Post’s David Ignatius on Wednesday.Senior Biden administration officials are still working to confirm whether the suspected attack was ordered by Kyiv, conducted by a rogue pro-Ukraine group, or a false flag operation by Russia, two U.S. officials said.If it was Ukraine, “we had no advance knowledge,” said one of th...

ECB may take smaller step, but won’t signal end of journey

Published Wed, 27 Nov 2024 13:56:07 GMT

FRANKFURT — The European Central Bank is expected to take its foot off the rate-tightening pedal by opting for a smaller rate hike of 0.25 percent on Thursday, while indicating that further rates are still to come.The ECB’s decision will follow on the heels of the U.S. Fed, which is also expected to hike by a modest 25 basis points later today but with the market predicting Chair Jerome Powell will signal a possible pause in tightening thereafter. “We believe the ECB may raise rates by 25 basis points and indicate an intention to hike further,” said Allianz Global Investors’ fixed income chief investment officer Franck Dixmier, referring to the outcome of the central bank’s rate-setting meeting. “While the U.S. Federal Reserve is almost at the end of its monetary policy tightening cycle, the European Central Bank is still far from any pivot.”A rate hike on Thursday would mark the seventh consecutive hike for the ECB, which has already lifted the key deposit rate from -0.5 per...