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Weight-loss drugs will be sold as pills, with just as many side effects and cost issues

Published Wed, 27 Nov 2024 10:30:07 GMT

Madison Muller | (TNS) Bloomberg NewsNovo Nordisk A/S and Eli Lilly & Co. are touting pill versions of their blockbuster weight-loss drugs that could come as soon as next year. But if you’re expecting something cheaper and with fewer side effects, think again.Obesity pills under development have some major shortcomings in ease of use and side effects that patients may not be prepared for. And if a tablet from Novo that’s already on the market is any guide, some will cost just as much as the injections that are already giving patients and insurers pause.Shots like Lilly’s Zepbound and Novo’s Wegovy are more than just fodder for late-night talk shows: They’re a gold mine that’s propelled the companies to dizzying valuations and lured other drugmakers into the field. Pfizer Inc. and AstraZeneca Plc are looking at oral medicines to make inroads into a market projected to reach $100 billion within seven years.“The orals will play a very significant role, because not everybody likes i...

Alex Barlow powers Duxbury past Marshfield in battle of Super Bowl teams

Published Wed, 27 Nov 2024 10:30:07 GMT

DUXBURY — Duxbury and Marshfield have Super Bowl games slated for Gillette Stadium, but the Patriot League titans were playing for the Keenan Division title prize Thursday at chilly Chandler Memorial Field.The Rams came in with a powerful offense, but it was running back Alex Barlow who made the most damage for the Dragons in their dramatic 23-21 win. Matt Landolfi’s Duxbury (10-1) squad won the Keenan title. Marshfield (9-3) was coming off a huge upset over two-time defending Super Bowl champion Catholic Memorial.Barlow was tremendous, as he bulled his way to a pair of 63-yard touchdown runs along with a five-yard jaunt. He finished with a monstrous 292 total yards. After accepting the offensive MVP award, he gave credit to the Dragons’ defense.“They said Marshfield’s the best offense in the state,” said Barlow. “We must be the best defense in the state.”Duxbury wasted no time at all running out to a 7-0 advantage. Zac Falls went high to pu...

Kelliher gets a win in his final game

Published Wed, 27 Nov 2024 10:30:07 GMT

HANSON – Everyone has their daily routine for the Thanksgiving Day holiday. The warm morning beverage and the smell of turkey and fixings in the oven. But while some things remain constant, the day for Abington head coach Jim Kelliher will never be the same.Kelliher left the field for the final time in his 50th season at the helm as his Green Wave rolled out the green carpet in his finale with a 46-6 resounding victory over rival Whitman-Hanson. Abington (8-3) upended the Panthers with six unanswered touchdowns, five in the second half, in the 112th meeting of the rivals.“You might see me mowing my lawn,” said Kelliher, who finishes his career on the sidelines at 313-209-8, fourth all-time on the list of All-Time Winningest Coaches in state history. “I don’t know if I’m going to be sleeping, might sit up all night and think about all the years. It’s going to be different but at the same time I’m going to be happy. Kids were mentally ready for this game and ready to handle anything t...

One way to reduce holiday stress: reframe gift traditions

Published Wed, 27 Nov 2024 10:30:07 GMT

By Annie Millerbernd | NerdWalletHave you made your holiday gift shopping list yet?Do you find that question stressful?Holiday shopping can bring up plenty of anxiety-inducing questions. What does the scent you pick for your sister-in-law’s candle say about what you think of her? Does your son still want the video game he mentioned in August? Why does a hair curling iron cost $600?More than half of holiday shoppers (55%) say buying gifts stresses them out, according to NerdWallet’s 2023 Holiday Shopping Report.To cut back on shopping stress, consider making gift-giving a smaller and less expensive part of your holiday. Traditions don’t change easily in many circles, so here are some tips to get you started.Communicate spending expectationsIf you want to change the way your group gives gifts, communicate your financial boundaries clearly, says Ambus Hunter IV, an accredited financial counselor based in Baltimore. This could mean setting a spending limit that’s lower than previous yea...

Catholic Memorial routs BC High, earns share of CC title

Published Wed, 27 Nov 2024 10:30:07 GMT

Zach Brown’s final high school football act was memorable.Brown rushed for 174 yards and two second-half touchdowns as Catholic Memorial pulled away from rival BC High for a 50-22 win on Thanksgiving Day at Murphy Family Stadium.The Knights’ win, coupled with Xaverian’s defeat of previously unbeaten St. John’s Prep, means the Catholic Conference finishes in a three-way tie.Brown’s standout performance was fitting for the Knights as the senior filled the void left behind by a litany of injured Knights.“The number of injuries we’ve had was incredible so that just makes it extra rewarding for Zach and the team today,” Catholic Memorial coach John DiBiaso said. “We’d prefer to be playing next week but it’s a good way to end for the seniors.”After the game was over, DiBiaso presented the game ball to 42-year assistant coach Mike Milo who has been by DiBiaso’s side for each of his 15 Super Bowls.“(Milo) ha...

Homelessness problem growing, shelter demand up 30%, staff at Pine Street Inn say

Published Wed, 27 Nov 2024 10:30:07 GMT

Needs at Boston’s Pine Street Inn are rising dramatically as the state is flooded with migrants and housing prices skyrocket, according to organizers.While the state’s shelter system is at or near its 7,500 family limit and Massachusetts housing prices on the rise with very little spare stock, the homeless shelter on Harrison Avenue in Boston is seeing an increase in requests for their meal and overnight services, according to Director of Communications Ross Condit.“We are seeing an increase of need this year over last,” Condit said. “It’s the migrants, but it’s also senior citizens, many of whom have been living in their homes for decades and then suddenly a new landlord jacks up the rent and they can’t afford it any longer.”The shelter currently provides permanent housing more than 900 individuals, according to President and Executive Director Lyndia Downie, but will soon expand to more than 1,000.Those people, she said, are the lucky ones. They have left the shelter system ...

Hoffmeister runs wild as Needham defeats Wellesley

Published Wed, 27 Nov 2024 10:30:07 GMT

WELLESLEY – With Needham football running so deep in third-generation running back Tate Hoffmeister’s bloodline, failing to win a game between the nation’s oldest public school rivals would’ve been a tough pill to swallow.But he’ll never have to.Hoffmeister rushed for 235 yards and three touchdowns in his final high school game Thursday morning, helping the Rockets (10-2) win the 136th edition of their Thanksgiving Day matchup against Wellesley, 21-7.The defense played a critical part with a pair of red zone stops, bringing the Frederick J. Gorman Centennial Trophy back to Needham for the first time since 2018.Wellesley still owns the 66-61-9 all-time record.“It means a lot,” said Rockets head coach Doug Kopsco. “We haven’t even had our team meeting yet because everyone is still clustered around the trophy. You see all the alumni coming back here, being a part of that. I wish we could’ve given that to them, but for them to share in that experience this year, it means everything.”“I’...

Search resumes for the missing after landslide leaves 3 dead in Alaska fishing community

Published Wed, 27 Nov 2024 10:30:07 GMT

WRANGELL, Alaska (AP) — Ground search teams returned Thursday to the site of a massive landslide that killed three to search for an adult and two juveniles who remain missing, officials said.K-9 teams plan to search along the waterline by small boat and will join ground teams in the slide area at multiple areas of interest, said Austin McDaniel, a spokesperson with the Alaska Department of Public Safety. Searchers used heat-sensing drones and a cadaver-dog on Wednesday but had no luck.Monday night’s slide churned up the earth from near the top of the mountain down to the ocean, tearing down a wide swath of evergreen trees and burying a highway in the island community of Wrangell, about 155 miles (250 kilometers) south of Juneau. Rescue crews found the body of a girl in an initial search Monday night and the bodies of two adults late Tuesday.Around 54 homes are cut off from town by the landslide, and roughly 35 to 45 people have chosen to stay in that area, interim borough manager Ma...

Driver charged for allegedly trying to run down Toronto parking enforcement officer

Published Wed, 27 Nov 2024 10:30:07 GMT

An arrest has been made related to an alleged road rage case involving a Toronto parking enforcement officer.Police were called to the area of Eglinton Avenue West and Atlas Avenue, west of Bathurst Street, where a parking enforcement officer was working on Nov. 9.Investigators say the accused was verbally abusive before getting into a vehicle and speeding away. He allegedly returned a few minutes later and deliberately drove toward the officer at a high speed before taking off again.The parking enforcement officer was not injured. Officers were called to the scene and located the suspect a short time later. On Nov. 10, police arrested and charged 22-year-old David Ariel Steinberg of Toronto with dangerous operation of a motor vehicle. He’s expected to appear in court on Dec. 22.

Federal COVID loan repayments could put St. Clair West store out of business: owner

Published Wed, 27 Nov 2024 10:30:07 GMT

A small business owner says federal COVID-19 loan repayments could force her to shut down her business and the Canadian Federal of Independent Businesses (CFIB) says she is not alone.Kym Klopp opened ecoexistance on St. Clair West 12 years ago to offer an alternative to conventional products with more eco-friendly options.Klopp said she has struggled to get the store back up-and-running since the COVID-19 lockdowns.“The day that we were allowed to open I had a massive flood here. So the whole upstairs fell into my store. So I was closed when it was going to be really great for people to come in for an additional two months.”She decided to keep going and signed a new lease this year.“I decided to sign that lease again because I’d say about in the last five years we’ve had 7,000 new residents move into the neighbourhood, strictly based on all the condominiums,” Klopp said.But with the Canadian Emergency Business Account (CEBA) loan repayment deadlin...